drug dosage guidelines veterinary saunders manual | Page 7

0.25–0.5mg/kg q6–8h IM, SC
Progesterone, repositol
See Medroxyprogesterone acetate
Promazine
Tranquazine
1–2mg/kg q6–8h IV, IM, PO
Promethazine hydrochloride
Phenergan
0.2–0.4mg/kg q6–8h IV, IM, PO (maximum dose: 1mg/kg)
Propantheline bromide
For detrusor hyperreflexia and urge incontinence:
Dog: 7.5–30.0 mg/dog q8–24h PO (start low)
Cat: 7.5mg/cat q24–72h PO
For diarrhea: 0.25mg/kg q8–12h PO
Propofol

2–6mg/kg IV for anesthesia (see Chap. 2)
Propranolol hydrochloride
Inderal
Dog: 20–60mg/kg over 5–10 min q8h IV, 0.2–1.0
mg/kg q8h PO
Cat: 2.5–5.0 mg/cat (0.4–1.2mg/kg) q8–12h PO
Prostaglandin E
See Misoprostol
Prostaglandin F2a
Lutalyse
Pyometra: Dog: 0.1–0.25 mg/kg, once daily for 3–5 days SC
(see Chap. 90)
Abortion:
(See Chap. 90 for protocol)
Psyllium
Metamucil
Dog: 1–3 tbsp/d (added to food)
Cat: 1–3 tsp/d (added to food)
Pyrantel pamoate
Nemex, Strongid
Dog: <2.5 kg: 10mg/kg PO >2.5 kg: 5mg/kg PO
Cat: 20mg/kg PO
Pyridostigmine bromide
Mestinon
Regonol
Antimyasthenic: 0.02–0.04mg/kg q2h IV, or 0.5–3.0mg/kg
q8–12h PO
Antidote (curariform): 0.15–0.3mg/kg IM, IV
Pyrimethamine
Daraprim
Dog: 1mg/kg q24h PO for 14–28 days (5 days for
Neosporum caninum)
Cat: 0.5–1.0 mg/kg q24h PO for 14–28 days
Quinacrine hydrochloride
Atabrine hydrochloride
Dog: 6.6 mg/kg q12h PO for 5 days
Cat: 11mg/kg q24h PO for 5 days
Quinidine gluconate
Quinaglute
Duraquin
Dog: 6–20mg/kg q6h IM; 6–20mg/kg q6–8h PO
(of base)
(324 mg quinidine gluconate = 202 mg quinidine base)
Quinidine polygalacturonate
Cardioquin
Dog: 6–20mg/kg q6h PO (of base)
(275 mg quinidine polygalacturonate = 167 mg quinidine
base)
Quinidine sulfate
Clin-Quin
Quinora
Dog: 6–20mg/kg q6–8h PO (of base)
(300 mg quinidine sulfate = 250 mg quinidine base)
Ranitidine
Zantac
Dog: 2mg/kg q8–12h IV, PO
Cat: 2.5 mg/kg q12h IV; 3.5mg/kg q12h PO
Retinoids
See Isotretinoin; Retinol; Etretinate
Retinol
Aquasol-A

625–800IU/kg q24h PO
Riboflavin (vitamin B2)
Dog: 10–20mg/d PO
Cat: 5–10mg/d PO
Rifampin
Rifadin
10–20mg/kg q24h PO
Ringer’s solution
40–50ml/kg/d IV, SC, IP for maintenance
requirements
Salicylate
See Acetylsalicylic acid (aspirin)
Selegiline
See Deprenyl (Anipryl)
Senna
Senokot
Cat: 5ml/cat q24h (syrup); 1/2 tsp/cat q24h with food
(granules)
SMS 201-995
Octreotide
10–20mg q8–12h SC
Appendix 1957
Sodium bicarbonate (NaHCO3)
Acidosis: 0.5–1.0 mEq/kg IV, monitor blood gases
(8.5% solution = 1 mEq/ml of NaHCO3)
Renal failure: 10 mg/kg q8–12h PO (adjust as necessary)
Alkalinization of urine: 50 mg/kg q8–12h PO (1 tsp is
approximately 2 g)
Sodium chloride (0.9%)
40–50ml/kg/d IV, SC, IP
Sodium chloride 7% (hypertonic saline)
2–8ml/kg/ IV for shock therapy
Sodium iodide (20%)
20–40mg/kg q8–12h PO
Sodium nitroprusside
See Nitroprusside sodium
Sodium thiomalate
See Gold sodium thiomalate
Sotalol
Betapace
Dog: 1–3.5mg/kg q12h PO
Cat: 1/8 of 80 mg tab q12h PO
Spironolactone
Aldactone
1–2mg/kg q12h PO
Stanozolol
Winstrol-V
Dog: 1–4mg/dog q12h PO; 25–50mg/dog/wk IM
Cat: 1mg/cat q12h PO; 25mg/cat/wk IM
Streptozotocin
(See Chapter 35 for administration protocol)
Sucralfate
Carafate
Dog: 0.5–1.0 g/dog q8–12h PO
Cat: 0.25 g/cat q8–12h PO
Sufentanil
Sufenta
2mg/kg IV, up to a maximum dose of 5mg/kg (premedicate
with acepromazine)
Sulfadiazine
100mg/kg IV, PO (loading dose), followed by 50mg/kg
q12h IV, PO (see also Trimethoprim)

Sulfadimethoxine
Albon, Bactrovet
55mg/kg PO (loading dose), followed by 27.5mg/kg q12h
PO (see also Primor)
Sulfaguanidine
100–200mg/kg q8h PO for 5 days
Sulfamethazine
100mg/kg PO (loading dose), followed by 50mg/kg q12h
PO
Sulfamethoxazole
Gantanol
100mg/kg PO (loading dose), followed by 50mg/kg q12h
PO
Sulfamethoxazole plus trimethoprim
Bactrim
Septra
See Trimethoprim plus sulfadiazine
Sulfasalazine (Sulfapyridine plus mesalamine)
Azulfidine (U.S.)
Salazopyrin (Canada)
Dog: 10–30mg/kg q8–12h PO
Cat: 10–20mg/kg q12–24h PO
(See also Mesalamine, Olsalazine)
Sulfisoxazole
Gantrisin
50mg/kg q8h PO (urinary tract infections)
Tacrolimus
Prototopic (ointment)
Apply topically q24h
Taurine
Dog: 250–500mg/dog q12h PO
Cat: 250mg/cat q12h PO
Tegaserod
Zelnorm
Dog: 0.05–0.1mg/kg q12h PO
Telezol
See Tiletamine plus zolazepam
Temaril-P (Trimeprazine plus prednisolone)
0.7–1.1 mg/kg (of trimeprazine) q12–24h PO
Tepoxalin
Zubrin
Dog: 10–20 mg/kg q24h PO then 10mg/kg q24h PO
Terbinafine
Lamasil
Dog: 30 mg/kg q24h PO for 21–28 days
Cat: 30–40 mg/kg q24h PO for 21–28 days
Terbutaline
Brethine, Bricanyl
Dog: 2.5–5.0mg/dog q8h SC, PO
Cat: 0.625mg/cat q12h SC, PO
Testosterone cypionate
Andro-Cyp
1–2mg/kg q2–4wk IM (see also Methyltestosterone)
Testosterone propionate
Testex
Malogen
0.5–1.0 mg/kg 2–3 times/wk IM (see also
Methyltestosterone)
Tetanus toxoid (equine antitoxin)
100–500U/kg (maximum 20,000U); IV slowly over 5–10
minutes
Tetracycline

Panmycin
Achromycin
15–22mg/kg q6–8h PO
4.4–11.0mg/kg q8–12h IV, IM
(See also Oxytetracycline, Doxycycline, Minocycline)
Theophylline
Dog: 9mg/kg q6–8h PO
Cat: 4mg/kg q8–12h PO
(See also Aminophylline)
Theophylline (long-acting)
Theo-Dur
Slo-bid Gyrocaps
Dog: 20mg/kg q12h PO (Theo-Dur) 30mg/kg q12h
PO (Slo-bid)
Cat: 25mg/kg q24h PO at night
Thiabendazole
Omnizole
1958 Appendix
Equizole
Dog: 50mg/kg q24h for 3 days, repeat 1 month
Cat (Strongyloides): 125mg/kg q24h for 3 days
Thiacetarsamine sodium
Caparsolate
2.2 mg/kg IV twice daily for 2 days
Thiamine (vitamin B1)
Dog: 10–100mg/dog/d PO
Cat: 5–30mg/cat/d PO (up to a maximum dose of
50mg/cat/d)
Thiomalate sodium
See Gold sodium thiomalate
Thiopental sodium
Pentothal
Dog: 6–10mg/kg IV (to effect)
Thiotepa
0.2–0.5mg/m2 intracavitary or IV
Thyroid hormone
See Levothyroxine, Liothyronine
Thyrotropin (TSH)
Thytropar
Dog: collect baseline sample, followed by 0.1IU/kg IV