drug dosage guidelines veterinary saunders manual | Page 6

Nitroglycerin ointment
Nitrol Ointment
Nitro-Bid Ointment
Nitrostat Ointment
(1 inch of ointment is approximately 15 mg)
Dog: 1/4–1 inch topically q12–24h
Cat: 1/4 inch topically q12–24h
Nitroprusside
Nipride
2.5–15mg/kg/min constant IV infusion
Nizatidine

Axid
2.5–5mg/kg q24h PO
Norfloxacin
Noroxin
22mg/kg q12h PO
Novobiocin
See Delta-Albaplex
Olsalazine
Dipentum
Dog: 20–30mg/kg q8–12h PO
Omega fatty acids
See also Derm Caps
1 capsule q12h PO (see also Essential fatty acids)
Omeprazole
Prilosec
Dog: 20mg/dog or 0.7–1.0mg/kg q24h PO
Cat: Not recommended
Ondansetron
Zofran
0.1–0.5mg/kg q6–12h IV, SC
0.5–1.0mg/kg q6–12h PO
o,p’-DDD
See Mitotane
Ormetroprim
See Primor
Oxacillin
Prostaphlin
Bactocill
22–40mg/kg q8h PO
Oxazepam
Serax
Appetite stimulant: 2.5mg/cat q12h PO
Oxtriphylline
Choledyl SA
Dog: 47mg/kg (equivalent to 30 mg/kg theophylline)
q12h PO
Oxybutynin chloride
Ditropan
5.0mg/dog q8–12h PO
Oxymetholone
Anadrol
1–5mg/kg q24h PO
Oxymorphone hydrochloride
Numorphan
Analgesia:
Dog: 0.05–0.1mg/kg IV 0.1–0.3mg/kg IM, SC
Cat: 0.01–0.04mg/kg IV 0.05–0.1mg/kg IM, SC
For preanesthesia or sedation: see Chapter 2
Oxytetracycline
Terramycin
20mg/kg q8h PO; 7.5–10.0mg/kg q8h IV
Oxytocin
Dog: 5–20 units/dog IM, repeat q30min for primary
inertia
Cat: 3–5 units/cat IM
2-PAM
See Pralidoxime chloride
Pamidronate
Aredia
1.3–2.0 mg/kg in 150 ml 0.9% saline in 2-hour IV infusion;
can repeat in 1–3 weeks
Pancreatic enzyme (pancrelipase)

Viokase
Pancrezyme
2 tsp per 20 kg body weight, or 1–3 tsp/0.45 kg of food,
mixed with food 20 minutes prior to feeding
Pancuronium bromide
Pavulon
0.1mg/kg IV
Pantoprazole
Protonix
0.7–1.0 mg/kg q24h IV, PO
Paregoric
Corrective Mixture
0.05–0.06mg/kg q12h PO (5ml of paregoric corresponds to
approximately 2 mg of morphine)
D-Penicillamine
Cuprimine
10–15mg/kg q12h PO
Penicillin G potassium
20,000–40,000 U/kg q6–8h, IV, IM
Penicillin G procaine
20,000–40,000U/kg q12–24h IM
Penicillin G sodium
20,000–40,000U/kg q6–8h IV, IM
Penicillin V
10mg/kg q8h PO
Pentazocine
Talwin
Dog: 1.65–3.3mg/kg q4h IM
Cat: 2.2–3.3mg/kg IV, IM, SC
Appendix 1955
Pentobarbital
Anesthesia: 25–30 mg/kg IV (first 1/2 of the dose
administered rapidly, then remaining administered to
effect)
Pentoxifylline
Trental
10–15mg/kg q8h PO
Petrolatum, white (flavored)
Laxatone
Cat: 1–5ml/cat q24h PO
Phenobarbital
Luminal
Dog: 2–8mg/kg q12h PO
Cat: 1–2mg/kg q12h PO
For seizures: Initially: 2.5mg/kg q12h PO (see Chap. 127)
and adjust by plasma concentration
Status epilepticus (dog or cat): 10–20 mg/kg IV (to effect)
or IV loading protocol (preferred; see Chap. 127)
Phenoxybenzamine hydrochloride
Dibenzyline
Dog: 0.25–0.5mg/kg q8h PO
Cat: 2.5mg/cat q8–12h PO
Phentolamine mesylate
Regitine (U.S.)
Rogitine (Canada)
0.02–0.1 mg/kg IV (as needed to maintain normal blood
pressure)
Phenylbutazone
Butazolidin
Dog: 10–15mg/kg q8h PO (maximum dose:
800 mg)
Cat: not recommended

Phenylephrine hydrochloride
Neo-Synephrine
0.01mg/kg q15min IV
0.1mg/kg q15min IM, SC
Phenylpropanolamine hydrochloride
Propagest
Dexatrim
Dog: 1–2mg/kg q12h PO
Cat: 1mg/kg q12h PO
Phenytoin
Dilantin
Antiepileptic in dog: 20–35mg/kg q8h PO
Antiarrhythmic in dog: 30mg/kg q8h PO or 10mg/kg IV
over 5 minutes
Phytonadione
See Vitamin K1
Phytomenadione
See Vitamin K1
Pimobendan
Vetmedin
Dog: 0.3–0.6mg/kg/d divided q12h PO
Piperazine
44–66mg/kg PO once
Piroxicam
Feldene
Dog: 0.3 mg/kg q48h PO (use cautiously)
Cat: dosage not established
Polyethylene glycol electrolyte solution
GoLYTELY
25ml/kg, then repeat in 2–4 hours PO
Polysulfated glycosaminoglycans
Adequan
1–2mg/kg IM once every 4 days for 7 injections
Potassium bromide
Dog and cat: 30 mg/kg q24h PO (in food) (see Chap.
127)
Potassium chloride
0.5 mEq/kg/d (do not administer at a rate faster than
0.5 mEq/kg/h)
10–40 mEq/500ml of fluids, depending on serum potassium
(see Chap. 5)
Potassium citrate
Urocit-K
Dog: 50–75mg/kg q12h PO
Potassium gluconate
Kaon elixir
Tumil-K
2.2 mEq/100 kcal of energy/day PO
Cat: 2–6 mEq/cat daily PO
Potassium iodide
30–100mg/cat daily (in single or divided doses) for 10–14
days
Potassium (or sodium) phosphate (potassium or sodium)
0.01–0.03 mmol phosphate/kg/hr for 3–6 hours (or,
2.5 mg/kg over 6 hours) (3mmol/ml or 93mg/ml
phosphate)
Pralidoxime chloride (2-PAM)
Protopam Chloride
Organophosphate toxicosis: 20 mg/kg q8–12h (initial dose
slow IV, or IM; subsequent doses IM, SC)
Praziquantel
Droncit

Dog (PO): <6.8 kg: 7.5mg/kg once >6.8 kg: 5mg/kg
once
Dog (IM, SC): ￡2.3 kg: 7.5mg/kg once 2.7–4.5 kg:
6.3mg/kg once ≥5kg: 5mg/kg once
Cat (PO): <1.8 kg: 6.3mg/kg once >1.8 kg: 5mg/kg
once
Cat (IM, SC): 5 mg/kg IM, SC paragonimiasis:
25mg/kg q8h for 2 days
Liver flukes: 20 mg/kg qd for 3 days; PO, SC
Prazosin
Minipress
0.5–2.0mg/animal q8–12h PO
Prednisolone
Anti-inflammatory:
Dog: 0.5–1.0mg/kg q12–24h IV, IM, PO initially then
taper to q48h
Cat: 2.2mg/kg q12–24h IV, IM, PO initially, then
taper to q48h
Immunosuppressive (dog and cat): initially 2.2–6.6mg/kg/d
IV, IM, PO, then taper to 2–4mg/kg q48h
Prednisolone sodium succinate
Solu-Delta-Cortef
Shock: 15–30mg/kg IV, then repeat in 4–6 h
CNS trauma: 15–30mg/kg IV, then taper to 1–2mg/kg
q12h
1956 Appendix
Prednisone
See Prednisolone
Primidone
Mylepsin
Mysoline
Initial dosage: 5–10mg/kg q8h PO
Primor (ormetroprim plus sulfadimethoxine)
25mg/kg on first day, followed by 12.5mg/kg q24h PO
Procainamide
Pronestyl
Dog: 10–20mg/kg q6h PO (maximum dose:
40mg/kg); 8–20mg/kg IV, IM; 25–50mg/kg/min IV
infusion
Cat: 3–8mg/kg IM, PO q6–8h
Procainamide (extended-release tablets)
Procan-SR
Dog: 20–50mg/kg q8h PO
Cat: 62.5mg/cat q8h PO
Prochlorperazine
Compazine