drug dosage guidelines veterinary saunders manual | Page 2

Clarithromycin
Biaxin
5mg/kg q12h PO
Clavamox
See Amoxicillin plus clavulanate
Clavulanate
See Amoxicillin plus clavulanate
Clemastine
Tavist, Contac 12-Hr Allergy
Dog: 0.05–0.1mg/kg q12h PO
Clindamycin
Antirobe
Cleocin
Dog: 5–10mg/kg q8h PO, IV, IM
Cat: 5.5 mg/kg q12h, or 11mg/kg q24h
(staphylococcal infections) PO; 11 mg/kg q12h, or
22mg/kg q24h PO(anaerobic infections) PO
Toxoplasmosis: 25–50 mg/kg/d PO (in divided treatments)
for 2–3 weeks
Clofazimine
Lamprene
10mg/kg q24h PO
Clomipramine
Anafranil, Clomicalm
1mg/kg q12–24h PO up to a maximum dose of 3mg/kg
q12–24h PO
Clonazepam
Klonopin
0.5mg/kg q12h PO
Clorazepate dipotassium
Tranxene
2mg/kg q12h PO

Clotrimazole (1%)
Lotrimin
Topical intranasal infusion; 50–60 ml per side over
1 hour via indwelling catheter (for aspergillosis,
penicilliosis)
Cloxacillin sodium
Cloxapen
Orbenin
Tegopen
20–40mg/kg q8h PO
Cod liver oil
1 tsp/10 kg once daily PO
Codeine
Dog: Analgesic: 0.5–1.0mg/kg q6–8h PO
Antitussive: 1–2mg/kg q6–12h PO
Colchicine
0.025–0.03mg/kg q24h PO
Corticotropin gel (ACTH)
Acthar
Response test: collect pre-ACTH sample and inject 2.2
IU/kg IM; collect post-ACTH sample at 2 hours in dogs
and at 1 and 2 hours in cats
Cosyntropin
Cortrosyn
Response test: collect pre-ACTH sample and inject 5mg/kg
IV in dogs and 125mg IV in cats; collect post-ACTH
sample at 1 hour
Cyanocobalamin (vitamin B12)
Dog: 100–200mg/dog qd PO
Cat: 50–100mg/cat qd PO
Cyclophosphamide
Cytoxan
Anticancer therapy: 50mg/m2 q48h PO, or 50mg/m2 once
daily 4 days/week PO, or 100–300mg/m2 IV and repeat in
21 days (see Chap. 26)
Immunosuppressive therapy: 50mg/m2 q48h PO
(see Chap. 24)
Cat: 200mg/m2 q2–3wk PO (see Chap. 26)
Cyclosporine
Sandimmune, Neoral, Optimmune ointment
Dog: 10mg/kg q12h PO
Cat: 5mg/kg q12h PO to 15mg/kg q24h (adjust dose
via monitoring)
Perianal fistulae: 1.75–3.0mg/kg q12h PO
Topical treatment for keratoconjunctivitis sicca: 1–2%
solution in oil: instill 1 drop in eye q12hr
Cyclothiazide
Anhydron
0.5–1.0mg/kg q24h PO
Cyproheptadine
Periactin
Antihistamine: 0.5–1.0mg/kg q12h PO
Appetite stimulant in cat: 2mg/cat q12h PO
Appendix 1947
Cytosine arabinoside
Cytosar
Dog: 100mg/m2 once daily for 4 days IV, SC
(lymphoma) q3–4wk (see Chap. 26)
Cat: 100mg/m2 IV or SC once daily for 2 days (see
Chap. 26)
Dacarbazine
DTIC

Dog: 1000mg/m2 IV drip for 6–8 hours, repeat q3wk
(see Chap. 30)
Danazol
Danocrine
5–10mg/kg q12h PO
Dantrolene sodium
Dantrium
Dog: 1–5mg/kg q8h PO
Cat: 0.5–2.0mg/kg q12h PO
Dapsone
1.1mg/kg q8h PO
Deferoxamine mesylate
Desferal
10mg/kg IV, IM q2h for 2 doses, then 10 mg/kg q8h for 24
hours
Delta-Albaplex (novobiocin plus prednisolone plus
tetracycline hydrochloride)
Dog 3–7kg: 1–2 tablets/d PO
Dog 7–14kg: 2–4 tablets/d PO
Dog 14–27kg: 4–6 tablets/d PO
Dog >27kg: 6–8 tablets/d PO
Cat: 1 tablet q12h PO
Deprenyl (L-deprenyl, selegiline)
Anipryl
Dog: 1mg/kg q24h PO
Deracoxib
Deramaxx
Dog: 3–4 mg/kg q24h PO for ￡7 days
Derm Caps (omega fatty acid)
1 capsule/9.1 kg daily PO
Desmopressin acetate
DDAVP
Diabetes insipidus: 2–4 drops q12–24h intranasally
von Willebrand’s disease: 1.0mg/kg SC, IV, diluted in 20ml
saline over 10 minutes
Desoxycorticosterone pivalate (DOCP)
Percorten-V
1.5–2.2mg/kg q25d IM
Dexamethasone
Azium
Anti-inflammatory: 0.1–0.2mg/kg q12–24h IV, IM, PO
Shock: 2.2–4.4mg/kg IV
Dexamethasone sodium phosphate
Shock: 1–2mg/kg IV
Dextran-70
Gentran-70
10–20ml/kg IV q24h to effect
Dextromethorphan
Benylin DM and others
0.5–2.0mg/kg q6–8h PO
Dextrose (5% solution)
40–50ml/kg q24h IV
Diazepam
Valium
Preanesthetic: 0.1–0.25mg/kg IV, IM, SC
Status epilepticus: 0.25–0.5 mg/kg IV; repeat if necessary; 1
mg/kg rectally
Appetite stimulant in cat: 0.1–0.2 mg/kg IV (q12–24h as
needed)
Functional urethral obstruction in dogs: 2–10mg/dog q8h
PO
Urinary disorder in cat: 1.25–2.5mg/cat q8–12h PO

Diazoxide
Proglycem
10 mg/kg q12h PO, do not exceed 60mg/kg/d
Diclorophene
See Toluene
Dichlorphenamide
Daranide
2–4mg/kg q8–12h PO
Dichlorvos
Performer
Dog: 26.4–33mg/kg PO
Cat: 11mg/kg PO
Dicloxacillin
Dynapen
11–55mg/kg q8h
Dicyclomine
Bentyl
0.2 mg/kg q8–12h PO
Diethylcarbamazine
Caricide
Filaribits
Heartworm prophylaxis: 6.6mg/kg q24h PO
Diethylstilbestrol (DES)
Urinary incontinence (dog): 0.1–1.0mg/dog q24h PO for 3
days, then 1mg/wk PO
Digitoxin
Crystodigin
0.02–0.03mg/kg q8h PO
Digoxin
Lanoxin
Cardoxin
Dog: 0.22mg/m2 q12h PO, 0.0055–0.01mg/kg q12h
PO, (reduce dose by 10% for elixir)
Cat: 0.01 mg/kg q48h, 0.007 mg/kg q48h (with Lasix
and aspirin)
Dihydrotachysterol (vitamin D)
Hytakerol
DHT
Initial: 0.02–0.03mg/kg/day PO maintenance:
0.01–0.02mg/kg q24–48h PO
Diltiazem hydrochloride
Cardizem
Dog: 0.5–1.5mg/kg q8h PO
Cat: 1.75–2.4mg/kg q8–12h PO
Dilacor XR
Cat: 30mg/cat q12–24h PO
Cardizem CD
Cat: 10mg/kg q24hr PO
Dimenhydrinate
Dramamine (U.S.)
1948 Appendix
Gravol (Canada)
Dog: 4–8mg/kg q8h IV, IM, PO
Cat: 12.5 mg q8h IV, IM, PO
Dimercaprol
BAL in oil
4mg/kg q4h IM
Dinoprost tromethamine
See Prostaglandin F2a
Dioctyl calcium sulfosuccinate
See Docusate calcium
Dioctyl sodium sulfosuccinate

See Docusate sodium
Diphenhydramine hydrochloride
Benadryl
2.2mg/kg q8–12h IV, IM, PO
Diphenoxylate hydrochloride
Lomotil
Dog: 0.1–0.2mg/kg q8–12h PO
Cat: 0.05–0.1mg/kg q12h PO
Diphenylhydantoin
See Phenytoin
Diphosphonate disodium etidronate
See Etidronate disodium
Dipyridamole
Persantine
4–10mg/kg q24h PO
Disopyramide phosphate
Norpace
Dog: 6–15mg/kg q8h PO
Dithiazanine iodide
Dizan
6.6–11.0 mg/kg q24h PO for 7–10 days
Divalproex sodium
Depakote
Equivalent to valproic acid (see Valproic acid)
Dobutamine
Dobutrex
Prepare 250 mg in 1 L 5% dextrose
Dog: 2.5–20mg/kg/min IV infusion
Cat: 2.5–5.0mg/kg/min