drug dosage guidelines veterinary saunders manual

Drug Dosage Guidelines
for Dogs and Cats
Appendix
10–20mg/kg q6–8h IV, IM, SC (ampicillin sodium)
Principen
20–40mg/kg q8h PO
Ampicillin trihydrate
Polyflex
6.5mg/kg q12h, IM, SC
Amprolium
Amprol
Corid
1.25 g of 20% amprolium powder added to daily feed, or
30ml of 9.6% amprolium solution to 3.8 L of drinking
water for 7 days
Amrinone lactate
Inocor
1–3mg/kg IV (loading dose) followed by 30–100mg/kg/min
IV infusion
Antacid drugs
See Aluminum hydroxide gel; Calcium carbonate;
Magnesium hydroxide
Apomorphine hydrochloride
0.02–0.04mg/kg IV, IM; 0.1 mg/kg SC; or instill 0.25 mg in
conjunctiva of eye (dissolve 6-mg tablet in 1–2 ml of
saline)
Ascorbic acid (vitamin C)
Diet supplement or for copper toxicity 100–500mg/animal
qd
Acetaminophen toxicity 30 mg/kg q6h for seven treatments,
PO, SC
L-Asparaginase
Elspar
10,000–30,000IU/m2 IM, SC, or IP as needed (pretreat with
antihistamines, steroids); see Chapter 26.
Aspirin
See Acetylsalicylic acid
Atenolol
Tenormin
Dog: 6.25–25mg/dog q12h PO or 0.25–1.0mg/kg
q12–24h PO
Cat: 6.25–12.5mg/cat q24h PO
Atracurium besylate
Tracrium
0.2 mg/kg IV initially, then 0.15mg/kg q30min (or IV
infusion at 3–8mg/kg/min)
Atropine
0.02–0.04mg/kg q6–8h IV, IM, SC
Organophosphate and carbamate toxicosis: 0.2–0.5mg/kg
(as needed)
Auranofin (triethylphosphine gold)
Ridaura
0.1–0.2mg/kg q12h PO
Aurothioglucose
Solganal
Dog <10kg: 1 mg/dog IM first week, 2mg/dog IM
second week, 1mg/kg/wk maintenance
Dog >10kg: 5 mg/dog IM first week, 10mg/dog IM
second week, 1mg/kg/wk maintenance

Cat: 0.5–1 mg/cat IM every 7 days
Azathioprine
Imuran
Dog: 2mg/kg q24h PO initially, then 0.5–1.0mg/kg
q48h
Cat: 0.3–0.5 mg/kg PO, q24–48h (q48h is preferred)
Azithromycin
Zithromax
Dog: 10mg/kg q24h PO ¥ 5 days or 3.3mg/kg q24h
PO ¥ 3 days
Cat: 5mg/kg q48h PO
AZT (azidothymidine)
See Zidovudine
Baclofern
Lioresal
Dogs: 1–2mg/kg q8h PO
BAL
See Dimercaprol
Benazepril
Lotensin
Dog: 0.5mg/kg q12–24h PO
Betamethasone1
Celestone
Betasone
0.1–0.2mg/kg q12–24h PO
Bethanechol chloride
Urecholine
Dog: 2.5–25.0mg/dog q8h PO
Cat: 2.5–5.0mg/cat q8h PO
Bicarbonate
See Sodium bicarbonate
Bisacodyl
Dulcolax
Dog: 5–20 mg qd PO
Cat: 5 mg qd PO
Bismuth subcarbonate
0.5–3.0 g q4h PO
Bismuth subsalicylate
Pepto-Bismol
1–3ml/kg/d (in divided doses) PO
Bleomycin sulfate
Blenoxane
10U/m2 IV or SC for 3 days, then 10U/m2 weekly
(maximum cumulative dose: 200U/m2)
Bromide
See Potassium bromide
Budesonide
Entocort
Dog: 1–3mg q24h PO
Cat: 1mg q24h PO
Bunamidine
Scolaban
20–50mg/kg PO
Bupivacaine hydrochloride
Marcaine
0.5mg/kg epidural
1mg/kg total dose for local nerve block
Buprenorphine
Temgesic
0.005mg/kg q4–8h IV, IM
Buspirone
BuSpar

Cat: 2.5–5mg/cat q12–24h PO
Appendix 1945
Butorphanol
Torbutrol
Torbugesic
Dog: Analgesic: 0.1–0.2mg/kg IV, 0.1–0.4mg/kg IM
or SC Antitussive: 0.55–1.1mg/kg PO q6–12h,
0.055–0.11mg/kg SC q6–12h
Cat: Analgesic: 0.05–0.2mg/kg IV, 0.1–0.3mg/kg IM,
SC
Calcitonin
Calcimar
4–6IU/kg SC initially q12h, then q8h for hypercalcemia
Calcitriol
Rocaltrol
2–3 ng/kg/d divided q12h for 3–4 days, then 1–2 ng/kg/d
maintenance
Calcium carbonate
25–50mg/kg/d PO
Camalox
60–100mg/kg/d (in divided doses) as phosphate binder
Calcium chloride (10% solution)
Hypocalcemia: 5–15mg/kg/h IV
Calcium citrate
Cat: 10–30mg/kg q8h (with meals) PO
Calcium disodium EDTA
See Edetate calcium disodium (CaNa2, EDTA)
Calcium gluconate (10% solution)
0.5–1.5 ml/kg IV (slowly)
Calcium gluconate tablets
25–50mg/kg/day PO
Calcium lactate
25–50mg/kg/d PO
Captan
0.25% solution topically, 2–3 times/wk
Captopril
Capoten
Dog: 0.5–2.0mg/kg q8–12h PO
Cat: 3.12–6.25mg/cat q8h PO
Carbenicillin disodium
Geopen
Pyopen
40–50mg/kg q6–8h IV, IM, SC
Carbenicillin indanyl sodium
Geocillin
Urinary tract infections: 10mg/kg q8h PO
Carbimazole
Neo-mercazole
Cat: 5mg/cat q8h PO (induction), followed by
5mg/cat q12h PO
Carboplatin
Paraplatin
Dog: 250–300mg/m2 q3wk IV
Cat: 150–250mg/m2 q4wk IV
Carnitine
See Levo-carnitine
Carprofen
Rimadyl
Dog: 2mg/kg q12h PO
Carvedilol
Coreg
See Chapter 146

Castor oil
Dog: 8–30ml/dog qd PO
Cat: 4–10ml/cat qd PO
Cefadroxil
Cefa-Tabs
Cefa-Drops
Dog: 22mg/kg q12h PO
Cat: 22mg/kg q24h PO
Cefazolin sodium
Ancef
Kefzol
20–25mg/kg q6–8h IV, IM
Cefepime
Maxipime
Dog: 40 mg/kg q6h IM, IV
Cefmetazole sodium
Zefazone
15mg/kg q8h IV, IM, SC
Cefotaxime sodium
Claforan
20–80mg/kg q6h IV, IM
Cefoxitin sodium
Mefoxin
15–30mg/kg q6–8h IV
Ceftazidime
Fortaz
30 mg/kg q6h IV, IM
Ceftiofur
Naxcel
Dog: 2.2–4.4 mg/kg q24h SC
Cephalexin
Keflex
10–30mg/kg q6–12h PO
Cephalothin sodium
Keflin
10–30mg/kg q4–8h IV, IM
Cephapirin sodium
Cefadyl
10–30mg/kg q4–8h IV, IM
Cephradine
Velosef
10–25mg/kg q6–8h PO
Charcoal, activated
Acta-Char
SuperChar Vet/Powder or Vet/Liquid
Toxiban
1–4 g/kg PO (granules)
6–12ml/kg PO (suspension)
Chlorambucil
Leukeran
2–4mg/m2 q48h PO (see Chap. 26)
Cats (FIP): 20mg/m2 q2–3 wk PO
Chronic lymphocytic leukemia
20mg/m2 q1–2wks PO or 6mg/m2/day
Chloramphenicol
Chloromycetin
Dog: 30–50mg/kg q6–8h IV, IM PO
Cat: 30–50mg/cat q12h IV, IM PO
1946 Appendix
Chlorothiazide
Diuril
20–40mg/kg q12h PO

Chlorpheniramine maleate
Phenetron
Chlor-Trimeton
Dog: 0.4mg/kg q8–12h PO
Cat: 2mg/cat q12h PO
Chlorpromazine
Thorazine
0.5mg/kg q6–8h IM, SC, PO
Prior to cancer chemotherapy: 2mg/kg q3h SC
Chlortetracycline
25mg/kg q6–8h PO
Cholecalciferol (vitamin D3)
500–2000U/kg/d PO (1 mg = 40,000U)
Chorionic gonadotropin
See Gonadotropin, chorionic (hCG)
Cimetidine
Tagamet
5–10mg/kg q6–8h IV, IM, PO
Renal failure: 2.5–5.0mg/kg q12h IV, PO
Ciprofloxacin
Cipro
5–15mg/kg q12h PO
Cisapride
Propulsid
Dog: 0.25–0.5mg/kg q8–12h PO
Cat: 2.5–5mg q8–12h PO
Cisplatin
Platinol
50–70mg/m2 q3wk IV drip (requires aggressive diuresis); do
not use in cats