armed, by our own ignorance and false shame, with a thousand times its actual power to destroy. Against all of these three great plagues medicine has pitted the choicest personalities, the highest attainments, and the uttermost resources of human knowledge. Against all of them it has made headway. It is one of the ironies, the paradoxes, of fate that the disease against which the most tremendous advances have been made, the most brilliant victories won, is the third great plague, syphilis--the disease that still destroys us through our ignorance or our refusal to know the truth.
We have crippled the power of tuberculosis through knowledge,--wide-spread, universal knowledge,--rather than through any miraculous discoveries other than that of the cause and the possibility of cure. We shall in time obliterate cancer by the same means. Make a disease a household word, and its power is gone. We are still far from that day with syphilis. The third great plague is just dawning upon us--a disease which in four centuries has already cost a whole inferno of human misery and a heaven of human happiness. When we awake, we shall in our turn destroy the destroyer--and the more swiftly because of the power now in the hands of medicine to blot out the disease. To the day of that awakening books like this are dedicated. The facts here presented are the common property of the medical profession, and it is impossible to claim originality for their substance. Almost every sentence is written under the shadow of some advance in knowledge which cost a life-time of some man's labor and self-sacrifice. The story of the conquest of syphilis is a fabric of great names, great thoughts, dazzling visions, epochal achievements. It is romance triumphant, not the tissue of loathsomeness that common misconception makes it.
The purpose of this book is accordingly to put the accepted facts in such a form that they will the more readily become matters of common knowledge. By an appeal to those who can read the newspapers intelligently and remember a little of their high-school physiology, an immense body of interested citizens can be added to the forces of a modern campaign against the third great plague. For such an awakening of public opinion and such a movement for wider co?peration, the times are ready.
JOHN H. STOKES.
ROCHESTER, MINN.
CONTENTS
PAGE
CHAPTER I
THE HISTORY OF SYPHILIS 11
CHAPTER II
SYPHILIS AS A SOCIAL PROBLEM 15
CHAPTER III
THE NATURE AND COURSE OF SYPHILIS 21 The Prevalence of Syphilis 24 The Primary Stage 26
CHAPTER IV
THE NATURE AND COURSE OF SYPHILIS (Continued) 35 The Secondary Stage 35
CHAPTER V
THE NATURE AND COURSE OF SYPHILIS (Continued) 45 Late Syphilis (Tertiary Stage) 45
CHAPTER VI
THE BLOOD TEST FOR SYPHILIS 54
CHAPTER VII
THE TREATMENT OF SYPHILIS 60 General Considerations 60 Mercury 62
CHAPTER VIII
THE TREATMENT OF SYPHILIS (Continued) 70 Salvarsan 70
CHAPTER IX
THE CURE OF SYPHILIS 80
CHAPTER X
HEREDITARY SYPHILIS 92
CHAPTER XI
THE TRANSMISSION AND HYGIENE OF SYPHILIS 109
CHAPTER XII
THE TRANSMISSION AND HYGIENE OF SYPHILIS (Continued) 121 The Control of Infectiousness in Syphilis 121 Syphilis and Marriage 125
CHAPTER XIII
THE TRANSMISSION AND HYGIENE OF SYPHILIS (Continued) 133 Syphilis and Prostitution 133 Personal Hygiene of Syphilis 136
CHAPTER XIV
MENTAL ATTITUDES IN THEIR RELATION TO SYPHILIS 141
CHAPTER XV
MORAL AND PERSONAL PROPHYLAXIS 156
CHAPTER XVI
PUBLIC EFFORT AGAINST SYPHILIS 164
INDEX 187
LIST OF ILLUSTRATIONS
PAGE PAUL EHRLICH [1854-1915] 69
FRITZ SCHAUDINN [1871-1906] 112
E. ROUX 161
��LIE METCHNIKOFF [1845-1916] 161
The Third Great Plague
Chapter I
The History of Syphilis
Syphilis has a remarkable history,[1] about which it is worth while to say a few words. Many people think of the disease as at least as old as the Bible, and as having been one of the conditions included under the old idea of leprosy. Our growing knowledge of medical history, however, and the finding of new records of the disease, have shown this view to be in all probability a mistake. Syphilis was unknown in Europe until the return of Columbus and his sailors from America, and its progress over the civilized world can be traced step by step, or better, in leaps and bounds, from that date. It came from the island of Haiti, in which it was prevalent at the time the discoverers of America landed there, and the return of Columbus's infected sailors to Europe was the signal for a blasting epidemic, which in the sixteenth and seventeenth centuries devastated Spain, Italy, France, and England, and spread into India, Asia, China, and Japan.
[1] For a detailed account in English, see Pusey, W. A.: "Syphilis as a Modern Problem," Amer. Med. Assoc., 1915.
It is a well-recognized fact that a disease which has never appeared among a people before, when it does attack them, spreads with terrifying rapidity and pursues a violent and destructive course on the new soil which they offer. This was the course of syphilis in Europe in the years immediately following the return of Columbus in 1493. Invading armies, always a fruitful
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